The Compatibility Gene PDF/EPUB ñ The Compatibility

The Compatibility Gene takes readers on a global journey of discovery spanning 60 years involving scores of scientists and encompassing the history of transplants and immunology That journey has revealed astonishing links between who we are as individuals and our never ceasing struggle to survive disease Most of the 25000 genes we possess are the same for all of us Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease In The Compatibility Gene distinguished immunologist Daniel Davis draws on new research to suggest a number of even fascinating and controversial conclusions about compatibility genes that we find others or less sexy according to their compatibility genes dating services are starting to match people in this way that the wiring between some neurons is kept or broken according to the activity of compatibility genes and that compatibility genes influence the chances of a couple having a successful pregnancy Profoundly personal life forming and life changing decisions appear to be governed by the actions of a few inherited genes Most importantly Davis proposes that because we each respond slightly differently to any particular disease in the not too distant future vaccines and other medications may be tailored to match our compatibility genes a revolutionary breakthrough in the fight against disease Including vivid portraits of the scientists who worked tirelessly to unlock the secrets of compatibility genes as well as patients who survived disease due to lucky genetic inheritances The Compatibility Gene explains an aspect of human biology that will undoubtedly have profound impacts on medical practice in the 21st Century

10 thoughts on “The Compatibility Gene

  1. says:

    I read this in a bit of a piecemeal fashion due to holidays so my impressions of it are probably a little scattered than usual It’s basically a book which combines immunology and genetics and even some neurology to discuss the way certain genes work in humans Since that’s right up my street I found this fascinating although I found some chapters really slow goingOne thing I’m not 100% a fan of is the personal details about some of the scientists because it’s not really relevant Whether a female scientist prioritises children or her career doesn’t have any effect on the importance of her findings and as a way of identifying motives for studying stuff it’s pretty weak Not everything has a personal connectionThe main thing I’m taking away from this book is that we still don’t know half there is to know about the immune system about genetics about our own bodies If that doesn’t speak to the importance of such research I don’t know what doesDid you know that dogs have a sexually transmitted cancer? Not just an oncovirus like HPV but a contagious cancerOriginally posted here Featuring the author dropping by to let me know that he's not being sexist by focusing on the fact that the female scientists he mentions don't have families but never replying when I asked why he didn't then make a big thing of it for male scientists tooETA Now featuring the author replying some although he mostly took it to twitter where he accused me of having an agenda

  2. says:

    A short compelling look at the immune system's major histocompatibility complex Davis effectively explains how the immune system recognises 'self' and 'non self' and thus effectively identifies disease within the body or on occasion fails to He also looks at the other ways that the 'compatibility genes' affect our body for instance there is an interesting section on the impact of the immune system on pregnancy He also details the major scientific achievements that led to these discoveries I could have done with slightly fewer appellations of 'hero' to the admittedly tireless and brilliant scientists of his narrative but overall it was an enjoyable and informative read

  3. says:

    Part two entitled The Frontier of Compatibility Gene Research saved this book for me Part one and part three were terrible Part one comprised a lot of back story on the who's who of this particular gene research I couldn't care less who did it or how they got there Tell me what the research results were and how it impacts society Part three was equally frustrating as it was supposed to be the popular science connection to our world and how this impact things we might be interested in such as sexual selection and pregnancy Which could have been interesting execpt that it wasn't so I dare to fault the author but perhaps this section was not fleshed out because there were not enough strong associations and so it was kind of a glimpse into what might be but isn't yet sound Anyway worth the read for part two Probably readable in the bookstore just that section if you have bit of time

  4. says:

    Some of the best popular science books tell us as much about the people as the science and that is the approach taken by Daniel Davis In exploring the ‘compatibility gene’ or accurately the ‘compatibility genes’ – I don’t know why it’s singular in the title He takes us on a voyage of discovery through the key steps to identifying the small group of genes that seem to contribute to making that individual or less compatible with other people whether on the level of transplants or sexual compatibility taking in our growing understanding of the immune system along the wayIt probably helps that Davis is a practising scientist in the field – the director of research at the University of Manchester’s Collaborative Centre for Inflammation Research and a visiting professor at Imperial College London Often frankly discovering the book is by a working scientist can mean turgid text or an inability to explain the science in a way the general reader can understand but Davis writes fluently and often beautifully as much in love with the history of his trade as the scientific breakthroughs he coversA good example of the way he brings a topic to life is the first subject to come under his spotlight the Nobel Prize winning Peter Medawar and his colleagues several of whom also get a good biographical introduction I’ve read before about Medawar’s work on rejection and compatibility in transplants but in Davis’ hands it’s almost as if you are talking to Medawar about his life and achievements giving a real insight into the bumpy process of scientific discoveryThe book divides into three looking at the scientific revolution in compatibility the frontier of compatibility and the ‘overarching system’ which includes the near notorious T shirt sniffing research and the remarkable suggestion that a couple having the right mix of compatibility genes can enhance their ability to have children All in all there’s a good mix of the relatively familiar and the surprising new all handled in Davis’ measured likeable phrasingI only really have two small niggles I’ve never written a review yet without any One is that I think Davis is almost too close to the subject and as a result perhaps gives it of a sense of importance than it deserves Of course from a medical viewpoint this is important work but the way he seems to put it up there with the work of Newton Darwin and Einstein perhaps overinflates its importance The other slight problem I have is that for me there is rather too much biography and not quite enough science It’s interesting that the lead endorsement in the press release is by Bill Bryson It sounds terrible but I’m only really interested in the biographies of a handful of key scientists and that apart I’d rather just have a quick sketch and get into the science in a bit depth – but I appreciate that this might be a very different opinion from that of many would be readersSo don’t be put off by that textbook like low key cover – this is a really interesting read about a fascinating area of genetics and medicine Recommended